Fragile Sites and X-Linked Retardation
作者:
HechtFrederick,
HechtBarbara K.,
GloverThomas W.,
期刊:
Hospital Practice
(Taylor Available online 1981)
卷期:
Volume 16,
issue 11
页码: 81-88
ISSN:2154-8331
年代: 1981
DOI:10.1080/21548331.1981.11946863
出版商: Taylor&Francis
数据来源: Taylor
摘要:
One of a recently discovered group of genetic anomalies, the“fragile X”chromosome, is now known to be a significant cause of inherited mental retardation in males. A dozen different fragile sites—areas of weakness at specific chromosomal loci—have been observed and identified in vitro, but only the fragile X is definitely associated with any expressed defect.
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