Active Rosette Test in Cutaneous Lymphoproliferative Disorders
作者:
M.G. Bernengo,
G. Capella,
I. Mascoli,
G. Zina,
期刊:
Dermatology
(Karger Available online 1977)
卷期:
Volume 154,
issue 6
页码: 342-349
ISSN:1018-8665
年代: 1977
DOI:10.1159/000251092
出版商: S. Karger AG
关键词: Mycosis fungoides;Pseudolymphoma;T and B lymphocytes;Active rosette (T-Ea);Total T lymphocyte (T-Et)
数据来源: Karger
摘要:
T and B peripheral blood lymphocytes were evaluated in 17 patients with clinical and histological evidence of mycosis fungoides and in ten patients with benign lymphoplasias of the skin. The T subpopulation (T-Ea) characterized by a rapid rosette formation with sheep erythrocytes was also measured in these patients. While both T-total population (T-Et) and T-Ea subpopulation were within the normal range in pseudolymphoma group, a statistically significant decrease was observed in T-Ea and T-Et populations in the mycosis fungoides group. Moreover, the decrease in T-Ea subpopulation was found in all cases under investigation, even when T-Et population was still at the normal levels. A close relation between T-Ea values and clinical status was observed. B and null cells were substantially unchanged in all patients.
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