Monoclonal Gammopathy of Undetermined Significance Predisposing toHelicobacter pylori‐Related Gastric Mucosa‐Associated Lymphoid Tissue Lymphoma
作者:
Antonio Tursi,
Maria Modeo,
期刊:
Journal of Clinical Gastroenterology
(OVID Available online 2002)
卷期:
Volume 34,
issue 2
页码: 147-149
ISSN:0192-0790
年代: 2002
出版商: OVID
关键词: Helicobacter pyloriinfection;MALT lymphoma;MGUS
数据来源: OVID
摘要:
&NA;Gastric mucosa‐associated lymphoid tissue (MALT)‐associated B‐cell proliferation may range from benign to malignant, andHelicobacter pyloriis the only identified critical antigenic stimulus to the development of gastric MALT. Monoclonal gammopathy of undetermined significance (MGUS) is characterized by B‐cell hyper‐activation and clonal expansion and is know to predispose to B‐cell malignancies. We report a patient with MGUS andH. pyloriinfection in whom we noted the progression of gastritis to acquired gastric MALT and gastric MALT to MALT lymphoma during a 3‐year follow‐up.
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