Color Doppler carries a special promise in the investigation of the sick child: the technique is noninvasive, rarely requires sedation and outlines vessels especially well, because of the ready penetration of the small body by the ultrasound beam. This article outlines the present application in pediatric abdominal, peripheral vascular and cerebral diseases of the child: liver and kidney diseases and transplantation; thrombosis of abdominal and peripheral vessels; tumors; identification of unknown structures; acute scrotal diseases; intra-cranial hemorrhage, infarction, and hydrocephalus. The clinical application of color Doppler ultrasound in Pediatrics are rapidly expanding and what we describe as “future possibilities” may already be reality soon after this work is published.