Factors Influencing the Relapse of Gastric Ulcers During H2‐Receptor Antagonist Maintenance Therapy
作者:
Katsunori SAIGENJI,
Yoshiteru AZUUMI,
Yasusi YOKOYAMA,
Takeshi ASHIHARA,
Wasaburo KOIZUMI,
Toshiharu MITSUHASHI,
Masahito OHIDA,
期刊:
Digestive Endoscopy
(WILEY Available online 1992)
卷期:
Volume 4,
issue 1
页码: 8-18
ISSN:0915-5635
年代: 1992
DOI:10.1111/j.1443-1661.1992.tb00221.x
出版商: Blackwell Publishing Ltd
关键词: recurrent gastric ulcer;endoscopic recurrence;H2‐receptor antagonist long‐term maintenance therapy
数据来源: WILEY
摘要:
Abstract:We performed H2‐receptor antagonist maintenance therapy for 2 years on 146 patients with healed gastric ulcers (including those with concurrent duodenal ulcers), and determined the cumulative endoscopic and symptomatic recurrence rates. We also investigated the factors involved in ulcer recurrence in the first 12 months of maintenance therapy. The cumulative endoscopic non‐recurrence rate was 70.0% at 12 months and 57.2% at 24 months, while the cumulative symptomatic non‐recurrence rate was 84.8% at 12 months and 75.0% at 24 months. The factors contributing to endoscopic recurrence were the presence of a concomitant disease, the presence of duodenal ulcer, the type of ulcer, and the endoscopic stage at healing. The factors related to symptomatic recurrence were smoking and the type of ulcer. Multivariate analysis showed that the type of ulcer, smoking, and the endoscopic stage at healing influenced the risk of recur
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