&NA;Since 1978, the authors have treated 11 patients with lesions of the ventral thoracic spine via a transpleural anterolateral approach. Each of the patients presented with pain and paraparesis, 8 had sensory dysfunction, and 6 had demonstrated sphincteric disturbances. All 11 had radiographic confirmation of anterior cord compromise, and each underwent an anterior decompression, with 8 requiring graft stabilization. There were no surgical mortalities, and the postoperative complications were limited. In follow‐up, 10 of the 11 patients had complete resolution of their preoperative pain and were able to ambulate independently, Remission of sensory disturbances was noted in 6 patients, and 5 regained sphincteric control. The authors have found that this approach is both safe and effective, with several advantages over conventional laminectomy and posterolateral techniques. (Neurosurgery14:26‐30, 1984)