Autosomal Dominant Polycystic Kidney Disease Complicated by Glomerulonephritis
作者:
M.T.A. Villar,
P. Bass,
G. Dewhurst,
J.M. Theaker,
J.R.E. Dathan,
期刊:
Nephron
(Karger Available online 1992)
卷期:
Volume 62,
issue 2
页码: 226-228
ISSN:1660-8151
年代: 1992
DOI:10.1159/000187038
出版商: S. Karger AG
关键词: Polycystic kidney disease;Glomerulonephritis;Proteinuria;nephrotic
数据来源: Karger
摘要:
Two patients with autosomal dominant polycystic kidney disease (ADPKD) and concurrent glomerulonephritis are described. Both developed nephrotic-range proteinuria and one showed a concomitant acceleration in the rate of decline of renal function. Subsequent open renal biopsy revealed membrano-proliferative type-1 and mesangio-proliferative glomerulonephritis, respectively. Nephrotic-range proteinuria in the presence of ADPKD, with or without an accompanying decline in renal function, should prompt further investigation to exclude coexisting glomerular disease.
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