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An XX male with a single STS gene dose

 

作者: P. Wieacker,   J. Voiculescu,   C.R. Müller,   H.H. Ropers,  

 

期刊: Cytogenetic and Genome Research  （Karger Available online 1983）
卷期: Volume 35, issue 1  

页码: 72-74

 

ISSN:1424-8581

 

年代: 1983

 

DOI:10.1159/000131841

 

出版商: S. Karger AG

 

数据来源: Karger

 

摘要:

There is substantial evidence that many XX males arise from an X/Y interchange, so that a terminal Xp segment carrying the Xg locus, but not the neighboring steroid sulfatase (STS) locus, is replaced by part of the Y chromosome. We show here that one of the two X chromosomes of an XX male with low intracellular levels of STS does not express the STS gene.

 

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