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fMRI reveals amygdala activation to human faces in social phobics

 

作者: Niels Birbaumer,   Wolfgang Grodd,   Oliver Diedrich,   Uwe Klose,   Michael Erb,   Martin Lotze,   Frank Schneider,   Ute Weiss,   Herta Flor,  

 

期刊: NeuroReport  （OVID Available online 1998）
卷期: Volume 9, issue 6  

页码: 1223-1226

 

ISSN:0959-4965

 

年代: 1998

 

出版商: OVID

 

关键词: Amygdala;Fear conditioning;Functional magnetic resonance imaging;Social phobia

 

数据来源: OVID

 

摘要:

FUNCTIONAL magnetic resonance imaging was used to determine the activation of the amygdala while seven social phobics and five healthy controls were exposed to slides of neutral faces as well as aversive odor stimuli. The amygdala was selectively activated in the social phobics during presentation of the face stimuli. The data show for the first time that the amygdala is active in human phobics when they are exposed to potentially fear-relevant stimuli. Further research is needed to determine the extent to which overactivation of the amygdala precedes or is a consequence of phobia.

 

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