首页   按字顺浏览 期刊浏览 卷期浏览 Ring Expansion Reactions of Acronycine to Fused 1,4-Oxazepine and 1,4-Dioxepin Systems
Ring Expansion Reactions of Acronycine to Fused 1,4-Oxazepine and 1,4-Dioxepin Systems

 

作者: Prokopios Magiatis,   Sofia Mitaku,   Alexios-Leandros Skaltsounis,   Fran¸ois Tillequin,   Alain Pierré,   Ghanem Atassi,  

 

期刊: Natural Product Letters  （Taylor Available online 2000）
卷期: Volume 14, issue 3  

页码: 183-190

 

ISSN:1057-5634

 

年代: 2000

 

DOI:10.1080/10575630008041229

 

出版商: Taylor & Francis Group

 

关键词: Acronycine;acridone;cytotoxicity;Baeyer-Villiger.

 

数据来源: Taylor

 

摘要:

Baeyer-Villiger oxidation of acronycine and 2-nitroacronycine led to 6-methoxy-3,3,13-trimethyl-8,13-dihydro-3H-chromeno[5,6-b][4,1]benzoxazepin-8-one (4) and 6-methoxy-3,3,13-trimethyl-2-nitro-8,13-dihydro-3H-chromeno[5,6-b][4,1]benzoxazepin-8-one (6), respectively. Lead tetraacetate oxidation ofcis-1,2-dihydroxy-1,2-dihydroacronycine followed by treatment with sodium borohydride afforded 3-hydroxy-7-methoxy-4,4,13-trimethyl-3,4,8,13-tetrahydro-1H-[1,4]dioxepino[5,6-c]acridin-8-one (13).

 

点击下载:  PDF (400KB)



返 回