Amino Acid Tablet-Substituted Diets in the Management of Chronic Renal Failure
作者:
H.A. Lee,
P.F. Down,
E. Fowell,
B.E.H. Hyne,
期刊:
Annals of Nutrition and Metabolism
(Karger Available online 1974)
卷期:
Volume 17,
issue 3
页码: 154-165
ISSN:0250-6807
年代: 1974
DOI:10.1159/000175532
出版商: S. Karger AG
关键词: Amino acid tablet diets;Chronic renal failure
数据来源: Karger
摘要:
Low protein Giovannetti diets in three patients with chronic renal failure have been compared with isonitrogenous, iso-caloric amino acid tablet-substituted regimes. Another patient has been managed on such a regime after regular haemodialysis treatment had to be suspended. The amino acid diets proved palatable and were effective in maintaining nitrogen balance when the caloric supply was adequate. Improved nitrogen balance correlated with diminished faecal nitrogen excretion and falling or stable blood urea levels implying improved urea nitrogen re-utilization. It is suggested that when the caloric supply is adequate for generation of sufficient α-ketonic acid derivatives, ammonia nitrogen is preferentially utilized for the synthesis of non-essential amino acids rather than more urea formation. Metabolic acidosis is a potential hazard of such regimes
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