首页   按字顺浏览 期刊浏览 卷期浏览 Molecular Mechanisms in the Regulation of Renal Proximal Tubular Na/Phosphate Cotranspo...
Molecular Mechanisms in the Regulation of Renal Proximal Tubular Na/Phosphate Cotransport

 

作者: Heini Murer,   Marius Lötscher,   Brigitte Kaissling,   Jürg Biber,  

 

期刊: Kidney and Blood Pressure Research  （Karger Available online 1996）
卷期: Volume 19, issue 3-4  

页码: 151-154

 

ISSN:1420-4096

 

年代: 1996

 

DOI:10.1159/000174063

 

出版商: S. Karger AG

 

关键词: Brush border membrane;Proximal tubule;Phosphate reabsorption;Parathyroid hormone;Low-phosphate diet;X-linked hypophosphatemia

 

数据来源: Karger

 

摘要:

Renal proximal tubular Na/phosphate cotransport is the key target in the control of renal phosphate handling. Using molecular tools for the type II Na/phosphate cotransporter, it could be documented that altered brush border membrane phosphate transport reflects a state of altered brush border expression of the specific transporter molecule. This alteration is either the consequence of specific membrane insertion/retrieval processes and/or reflects states of altered synthesisdegradation of the transporter.

 

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