IgM Nephropathy: Morphological Study Related to Clinical Findings
作者:
Juri Kopolovic,
Yigal Shvil,
Avishalom Pomeranz,
Noemi Ron,
Dvora Rubinger,
Ran Oren,
期刊:
American Journal of Nephrology
(Karger Available online 1987)
卷期:
Volume 7,
issue 4
页码: 275-280
ISSN:0250-8095
年代: 1987
DOI:10.1159/000167485
出版商: S. Karger AG
关键词: IgM nephropathy;Glomerulonephritis;Nephrotic syndrome;Mesangial IgM deposition;Minimal changes
数据来源: Karger
摘要:
This study describes 10 cases of IgM nephropathy in whom the main morphological findings consisted of diffuse mesangial deposition of IgM and varying degrees of mesangial cell proliferation. In addition, focal segmental sclerosis was present in 1 patient and global sclerosis in another. An ill-defined electron-dense deposit was seen within the mesangial area in 1 case. Except for 1 patient, who had hematuria only, all suffered from nephrotic syndrome without deterioration of renal function. In view of the constant and characteristic finding of a diffuse mesangial IgM deposition, it is suggested that this form of nephropathy constitutes an entity separate from focal glomerulosclerosis or minimal change disease.
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