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Parathyroid Function And Urinary Cyclic 3‘5’Adenosine Monophosphate

 

作者: NutteN. De,   DebackerM.,   VerbeelenD.,   ManderlierT.,   SixR.,   CorvilainJ.,  

 

期刊: Acta Clinica Belgica  （Taylor Available online 1975）
卷期: Volume 30, issue 2  

页码: 91-100

 

ISSN:1784-3286

 

年代: 1975

 

DOI:10.1080/17843286.1975.11716980

 

出版商: Taylor&Francis

 

关键词: Urinary cyclic AMP;Hypercalcemia;Hyperparathyroidism;Hypoparathyroidism;Paraneoplastic syndrome

 

数据来源: Taylor

 

摘要:

SummaryPatients with hypercalcemie primary hyperparathyroidism excrete more cyclic AMP than normal suhjects: 8.27±0.19μmoles/24 hr or 9.03±0.92μmoles/g creatinine.The excretion in hypoparathyroidism is lower than in normal volunteers: 3.07±0.30μmoles/24 hr or 2.86±0.36μmoles/g creatinine.Patients with hypercalcemia of non-parathyroid origin excrete less c-AMP than normals: 2.85±0.39μmoles/24 hr or 2.73±0.39μmoles/g creatinine.The principal clinical use of the determination of urinary c-AMP seems to be the differentiation of hypercalcemia of non-parathyroid origin and hypercalcemia due to PTH-like substances secreted by malignant tumors.

 

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