Do matrix metalloproteinases MMP-2 and MMP-9 (gelatinases) play a role in renal development, physiology and glomerular diseases?
作者:
Brigitte Lelongt,
Bruno Legallicier,
Rémi Piedagnel,
Pierre Ronco,
期刊:
Current Opinion in Nephrology and Hypertension
(OVID Available online 2001)
卷期:
Volume 10,
issue 1
页码: 7-12
ISSN:1062-4821
年代: 2001
出版商: OVID
数据来源: OVID
摘要:
Metalloproteinases MMP-2 and MMP-9 (also called gelatinases) are involved in cell invasion and in embryonic development and organogenesis. A growing number of reports suggest that MMP-2 and MMP-9 play some role in renal development, renal tubule physiology and glomerular pathophysiology. This editorial will focus on recent controversial data, especially those obtained from studies on MMP-9-deficient mice, which shed new light on the functions of gelatinases in normal and diseased kidneys.
点击下载:
PDF
(117KB)
返 回