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1,2‐Asymmetric induction when grignard reagents are added to of‐aminoketones. I. The influence of different factors and mechanisms of induction

 

作者: Antoine Gaset,   Marie‐Thérèse Maurette,   Armand Lattes,  

 

期刊: Journal of Applied Chemistry and Biotechnology  (WILEY Available online 1975)
卷期: Volume 25, issue 1  

页码: 1-12

 

ISSN:0375-9210

 

年代: 1975

 

DOI:10.1002/jctb.5020250102

 

出版商: John Wiley&Sons, Ltd

 

数据来源: WILEY

 

摘要:

AbstractThe problem of 1,2‐asymmetric induction has been studied as Grignard reagents were added to α‐aminoketones. The experimental factors have been modified in terms of the hypothesis of an interaction between the amino function and the Grignard reagents. The variations resulting from these changes have enabled an interpretation to be put forth of the phenomena depending on the equilibrium between a dipolar and a cyclic m

 

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