Prevalence of Antibodies against Hepatitis C Virus in a Dialysis Unit
作者:
P. Cantù,
S. Mangano,
M. Masini,
A. Limido,
G. Crovetti,
C. De Filippo,
期刊:
Nephron
(Karger Available online 1992)
卷期:
Volume 61,
issue 3
页码: 337-338
ISSN:1660-8151
年代: 1992
DOI:10.1159/000186931
出版商: S. Karger AG
关键词: Dialysis;Hepatitis C virus;Anti-HCV antibody
数据来源: Karger
摘要:
Anti-HCV was tested in 77 uremic patients, 48 on hemodialysis (HD), 29 on CAPD, by immunoenzymatic 1st and 2nd generation assays (ELISA I, II) and 4-antigen (4-RIBA) immublotting. The investigation was extended to the staff (n = 29) and to HCV-positive patients’ families (n = 30). The prevalence using 2nd generation tests was double (21%) that in 1 st generation tests (11%). A greater incidence in the HD than in the CAPD group (23 vs. 17%) and a highly significative correlation to dialytic age were observed. No one among the sanitary personnel and only 2 family members were found HCV positive, suggesting a low infectivity via the parenteral inevident route. Extracorporeal circulation and particularly the exposure time to the treatment seem to be the main risk factor
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