Role of CA125 and Abdominal Pelvic Computerized Axial Tomogram in the Monitoring of Chemotherapy Treatment of Ovarian Cancer
作者:
NganHextan Y.S.,
WongLing C.,
ChanStephen Y.W.,
MaHo K.,
期刊:
Cancer Investigation
(Taylor Available online 1990)
卷期:
Volume 8,
issue 5
页码: 467-470
ISSN:0735-7907
年代: 1990
DOI:10.3109/07357909009012069
出版商: Taylor&Francis
数据来源: Taylor
摘要:
AbstractTwenty four patients with epithelial ovarian cancer, who were treated by chemotherapy after debulking surgery, were monitored by serial monthly CA125 estimation and half-yearly computerized axial tomogram (CAT) of abdomen and pelvis. The efficiency of these monitoring methods and that of clinical examinaton were compared. The use of CA125 alone was superior to the use of clinical assessment alone in the detection of tumor progression (p0.05). Hence, CAT examination should not be used routinely to detect recurrence of tumor in patients without a raised CA125 level. However, in patients with Increased CA125 level, CAT examination had a place in locating and in determining the extent of the tumor which in selected patients may enable us to make changes in therapy without laparotomy and in other patients may help us to make a better assessment on whether further debulking is possible.
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