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Synthesis of 11-Methoxy Anthracyclines

 

作者: Agnès Génot,   Jean-Claude Florent,   Claude Monneret,  

 

期刊: Journal of Carbohydrate Chemistry  （Taylor Available online 1991）
卷期: Volume 10, issue 1  

页码: 91-95

 

ISSN:0732-8303

 

年代: 1991

 

DOI:10.1080/07328309108543893

 

出版商: Taylor & Francis Group

 

数据来源: Taylor

 

摘要:

Doxorubicin and daunorubicin are clinically important antitumor antibiotics but their use is restricted, especially for long-term treatment by their toxicity.1Hence the cardiotoxic side effects associated with these drugs have stimulated the search for analogues with lower cardiotoxicity, improved antitumor activity and lack of cross-resistance.

 

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