The Webb (Wb) Antigen in South Wales Donors
作者:
L. Bloomfield,
G.P. Rowe,
Carole Green,
期刊:
Human Heredity
(Karger Available online 1986)
卷期:
Volume 36,
issue 6
页码: 352-356
ISSN:0001-5652
年代: 1986
DOI:10.1159/000153659
出版商: S. Karger AG
关键词: Blood groups;Infrequent red-cell antigen;Webb antigen
数据来源: Karger
摘要:
Eight Webb antigen Wb+ propositi, 2 in the same family, were found in testing 10,117 random blood donors in South Wales with anti-Wb serum. Family studies on the new propositi confirmed the Wb antigen to be inherited as an autosomal dominant character. Wb segregated independently from ABO, Rh, MNSs, K, Fy, Jk, and was not X- or Y-borne; for the first time Wb was shown to be independent of Lu. Wb antigen was destroyed by some proteolytic enzymes and by neuraminidase. Sera from 5,144 random donors were screened with Wb+ cells resulting in detection of 2 additional anti-Wb.
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