SummaryWitloof chicory (Cichorium intybusL.) is tolerant to propyzamide and common amaranth (Amaranthus retroflexusL.) is sensitive. The absorption, translocation, and metabolism of propyzamide was studied in seedlings of witloof chicory and common amaranth to determine if differences in these processes cause the differential sensitivity. At 24,48, and 72 h after root treatment, there was no difference in the concentration of14C (g−1plant dry wt) in com‐mon amaranth and witloof chicory. Approximately 50% of the absorbed14C was translocated out of the roots to shoots of both species at 24 and 48 h after treatment. After 72 h about 55 and 74% of the absorbed14C was translocated to shoots of witloof chicory and common amaranth, respectively. Distribution of14C (g−1plant dry wt) in plant parts of witloof chicory and common amaranth seedlings was similar. Roots of both species accumulated the highest concentration of total14C, whereas shoots contained the lowest. Thin layer chromatography revealed that the herbicide was metabolized in neither species 48 h after treatment. No differences were found in absorption, translocation, or metabolism between witloof chicory and common amaranth with regard to propyz