AbstractOne‐dimensional V2O5nanowires have been synthesized inside the channels of mesoporous silica SBA‐15 through chemical approach, which involves aminosilylation of silanol groups on the silica surface, anchoring of isopoly acid, H6V10O28. by neutralization of basic amine groups, and thermal decomposition. The formation and physicochemical properties of the nanowires were monitored and studied by TG‐DTA, variable temperaturein situXRD, TEM, N2sorption measurements and UV‐Vis DRS. The results indicate that V2O5nanowires formed within SBA‐15 channels belong to orthorhombic polycrystal domains. The oxygen‐to‐metal charge transfer band of V2O5nanowires shows a blue shift in comparison with bulk V2O5, which clearly exhibits the quantum size effect