Spectrophotometric Simultaneous Analysis of Analgin – Adamon Mixture in Injection Preparations
作者:
Nevin Acar,
Feyyaz Onur,
期刊:
Analytical Letters
(Taylor Available online 1996)
卷期:
Volume 29,
issue 5
页码: 763-773
ISSN:0003-2719
年代: 1996
DOI:10.1080/00032719608001782
出版商: Taylor & Francis Group
关键词: Analgin;adamon;pharmaceutical preparation;spectrophotometry
数据来源: Taylor
摘要:
A new method is described for analyzing a binary mixture of analgin and adamon using extractive and derivative spectrophotometry. In the method, analgin and adamon both were extracted into chloroform as an ion-pair with thymol blue from their aqueous solution buffered to pH 3.6. Determination of these drugs was performed by reading the dA/dλ values at 600.0 nm and 310.5 nm in the first derivative spectra of the chloroform layer. Relative standard deviations of the method are 0.10% for analgin and 0.81% for adamon. The method was successfully applied to an injection solution containing these two active ingredients.
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