Femoral central venous catheter-associated deep venous thrombosis in children with diabetic ketoacidosis
作者:
Juan Gutierrez,
Rochelle Bagatell,
Meredith Samson,
Andreas Theodorou,
Robert Berg,
期刊:
Critical Care Medicine
(OVID Available online 2003)
卷期:
Volume 31,
issue 1
页码: 80-83
ISSN:0090-3493
年代: 2003
出版商: OVID
关键词: diabetic ketoacidosis;catheterization;central venous;venous thrombosis;shock;pediatrics;hyperglycemia;thrombophilia
数据来源: OVID
摘要:
ObjectiveTo describe the incidence of clinical deep venous thrombosis associated with femoral central venous catheters (CVC-DVT) in children with diabetic ketoacidosis (DKA).DesignRetrospective case-matched control series.SettingPediatric intensive care units of two university-affiliated hospitals.PatientsAll eight pediatric DKA patients with femoral central venous catheters between 1998 and 2001, and 16 age-matched control patients with femoral central venous catheters and circulatory shock.InterventionsNone.Measurements and Main ResultsThe records of all children with DKA and the control patients were reviewed. CVC-DVT was defined as persistent ipsilateral leg swelling after removal of a femoral central venous catheter. Control patients with coagulopathies, thrombocytopenia, cancer, and hyperglycemia were excluded. Four of eight patients with DKA developed CVC-DVT compared with none of the 16 control patients (p= .007, Fisher’s exact test). All four patients with DKA and CVC-DVT were <3 yrs old. Doppler ultrasound examination was performed on three of the four patients with clinical CVC-DVT, confirming the diagnosis in each case.ConclusionsThis study suggests that young children with DKA have an increased incidence of clinical DVT associated with the placement of femoral central venous catheters.
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