Perinatal Outcome Associated with PCP Versus Cocaine Use
作者:
TaborBannie L.,
SmithToni,
YonekuraMargaret Lynn,
期刊:
The American Journal of Drug and Alcohol Abuse
(Taylor Available online 1990)
卷期:
Volume 16,
issue 3-4
页码: 337-348
ISSN:0095-2990
年代: 1990
DOI:10.3109/00952999009001595
出版商: Taylor&Francis
数据来源: Taylor
摘要:
Phencyclidine (PCP) remains a widely used illicit drug, especially among adolescents and young adults. The pharmacologic effects of PCP are similar to those of cocaine; therefore, in this retrospective study 37 PCP-intoxicated parturients were matched for ethnicity, tobacco use, age, gravidity, and degree of prenatal care with 37 cocaine-intoxicated parturients. Infants exposed to PCPin uterolike those exposed to cocaine, had a high incidence of intrauterine growth retardation (32 vs 19%, N.S.), precipitate labor (43 vs 27%, N.S.), symptoms of neonatal drug withdrawal/intoxication, and prolonged neonatal hospitalizations. Moreover, they were more likely to have meconium-stained amniotic fluid (30 vs 19%,p=. 05) and less likely to be born prematurely as cocaine-exposed infants. The comparison between the long-term developmental outcome of these groups awaits further study.
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