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Sex chromatin in hair roots — 25 years later: fluorescence in situ hybridization of hair root cells for detection of numerical chromosome aberrations

 

作者: S. Lampel,   H. Steilen,   K.D. Zang,   B. Wullich,  

 

期刊: Cytogenetic and Genome Research  （Karger Available online 1993）
卷期: Volume 63, issue 4  

页码: 244-246

 

ISSN:1424-8581

 

年代: 1993

 

DOI:10.1159/000133543

 

出版商: S. Karger AG

 

数据来源: Karger

 

摘要:

The applicability of fluorescence in situ DNA hybridization to hair root preparations for the detection of numerical chromosome anomalies is demonstrated. This simple method yields a high number of scorable nuclei, allowing rapid identification of epithelial cell chromosome composition. In clinical genetics, this technique may become useful in cases where other types of cells are difficult to obtain.

 

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