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Treatment of advanced ovarian cancer: A randomised trial comparing adriamycin or 4′epi‐adriamycin in combination with cisplatin and cyclophosphamide

 

作者: W. R. Bezwoda,  

 

期刊: Medical and Pediatric Oncology  （WILEY Available online 1986）
卷期: Volume 14, issue 1  

页码: 26-29

 

ISSN:0098-1532

 

年代: 1986

 

DOI:10.1002/mpo.2950140107

 

出版商: Wiley Subscription Services, Inc., A Wiley Company

 

关键词: Adriamycin;4′epi‐adriamycin;ovarian cancer

 

数据来源: WILEY

 

摘要:

AbstractFifty‐one patients with ovarian cancer were entered in a randomised trial comparing treatment with cisplatin + adriamycin + cyclophosphamide (PAC) to cisplatin + 4′epi‐adriamycin + cyclophosphamide (PEC). Complete response rates for the two treatment arms were similar (9/27 PAC, 14/24 PEC). Patients with2 cm residual disease. Cardiotoxicity was significantly less in the PEC‐treated group (0/24) as compared with the PAC‐treated group (6/27, χ2= 4.0

 

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