Increased brain radioresistance after supralethal irradiation
作者:
Raymond L. Chaput,
Peter A. Berardo,
期刊:
Medical Physics
(WILEY Available online 2003)
卷期:
Volume 1,
issue 3
页码: 148-151
ISSN:0094-2405
年代: 2003
DOI:10.1118/1.1637287
出版商: American Association of Physicists in Medicine
数据来源: WILEY
摘要:
Clinical symptoms and performance were evaluated after shuttlebox‐trained miniature pigs received two 4400‐rad doses separated by time intervals of 10 − 4‐30 min. The doses were delivered to the head by 45‐MeV electrons from the AFRRI electron linear accelerator (LINAC). There was no significant difference in neurological symptons (Convulsions, coma, ataxia) or in performance after the second dose between animals that received the two doses 10 − 4or 0.3 min apart. As the time interval between doses was increased from 0.3 min, however, neurological symptoms declined and performance improved markedly after the second dose. When the doses were 30 min apart, the pigs showed no decrease in performance within the intial 30‐min postirradiation. It was concluded that more than physiochemical processes were involved in the increased radioresistance to the second dose of radiation.
点击下载:
PDF
(370KB)
返 回