The late onset of the intestinal complications of fibrocystic disease of the pancreas (mucoviscidosis) is described in a to‐year‐old boy and a 20‐year‐old man. Each presented with a palpable mass in the right iliac fossa. One patient had a right hemicolectomy, and the mass was found to be an accumulation of inspissated secretions firmly adherent to the caecal mucosa. In the second patient the mass disappeared with conservative treatment. The first patient had the further complication of multilobular biliary cirrhosis with a strikingly nodular liver. This unusual combination of lesions in a previously healthy boy caused diagnostic difficulties. The pathogenesis, prevention and treatment of these late intestinal and hepatic complications are di