Antidepressant‐Induced Rapid CyclingSix Case Reports
作者:
GERALD,
HUROWITZ MICHAEL,
LIEBOWITZ Domenic,
Ciraulo Section,
期刊:
Journal of Clinical Psychopharmacology
(OVID Available online 1993)
卷期:
Volume 13,
issue 1
页码: 52-56
ISSN:0271-0749
年代: 1993
出版商: OVID
数据来源: OVID
摘要:
We report six cases of rapid mood cycling induced by antidepressant treatment. The key to effective treatment involved the recognition of the pattern of apparent remission, relapse, antidepressant and/or stimulant adjustment, remission, relapse,etc. Hypomanic episodes were frequently mild and could be mistaken for remission. The destabilizing effects of antidepressant drugs were not corrected by the addition of mood stabilizers, necessitating the withdrawal of the antidepressant agent. All but one case responded to such withdrawal. Two cases required the addition of high-dose L-thyroxine for stabilization. Implications for an effective treatment protocol are discussed.
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