Alcohol ingestion‐induced, changes in the human rectal mucosaLight and electron microscopic studies
作者:
Steven Brozinsky,
Kazem Fani,
Saul Grosberg,
Simon Wapnick,
期刊:
Diseases of the Colon & Rectum
(OVID Available online 1978)
卷期:
Volume 21,
issue 5
页码: 329-335
ISSN:0012-3706
年代: 1978
出版商: OVID
数据来源: OVID
摘要:
&NA;Histologic and ultrastructural examination of specimens of rectal mucosa from 11 patients who had recently consumed excessive quantities of alcohol revealed marked pathologic changes. Goblet cells were decreased and a dense mononuclear cell infiltrate was seen on light microscopic study. Electron microscopy revealed swollen, distorted mitochondria and dilated and vesicular endoplasmic reticulum. These abnormalities disappeared after two weeks' abstinence. It is suggested that disordered organelle structure and function might contribute to the diarrhea frequently observed following excessive alcohol intake.
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