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Deficiencies in Factors IX and VIII: What Is Now Known

 

作者: KurachiKotoku,   NanShou,   FurukawaMidori,   KurachiSumiko,  

 

期刊: Hospital Practice  (Taylor Available online 1992)
卷期: Volume 27, issue 2  

页码: 41-51

 

ISSN:2154-8331

 

年代: 1992

 

DOI:10.1080/21548331.1992.11705358

 

出版商: Taylor&Francis

 

数据来源: Taylor

 

摘要:

Genetic defects both gross and subtle have recently been identified in about 900 patients with hemophilia A or B. The defects, which include deletions, insertions, and point mutations, reveal much about genetic structure-function relationships in hemophilia. These insights will lead to improved treatment of bleeding disorders and perhaps to their cure.

 

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