The residual effect of treatment with ivermectin after experimental reinfection with nematodes in calves
作者:
F. H. M. Borgsteede,
J. Hendriks,
期刊:
Veterinary Quarterly
(Taylor Available online 1986)
卷期:
Volume 8,
issue 2
页码: 98-104
ISSN:0165-2176
年代: 1986
DOI:10.1080/01652176.1986.9694029
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
The residual effect of treatment with ivermectin after experimental reinfection in calves was tested. Twenty‐four calves were divided into 6 groups of 4 calves each. All calves received a primary infection of 50,000 larvae of both Ostertagia ostertagi and Cooperia oncophora and 1000 Dictyocaulus viviparus larvae. Calves of group 1 remained untreated, and all other calves were treated 21 days after primary infection (0.2 mg/kg injected subcutaneously). Calves of groups 1 and 2 were slaughtered 7 days later. Calves of groups 3–6 were reinfected with the same number of larvae 3 days, I, 3 and 6 weeks after treatment respectively. Slaughter was 21 days after reinfection. Based on post‐mortem worm counts the efficacy of ivermectin after primary infection was 99.7% for O. ostertagi, 95.1% for C. oncophora and 100% for D. viviparus. A residual effect was present for at least one week, but could not be observed 3 weeks after treatment.
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