Sulfonamide Toxicity in Brook Trout
作者:
E.M. Wood,
W.T. Yasutake,
S.F. Snieszko,
期刊:
Transactions of the American Fisheries Society
(Taylor Available online 1955)
卷期:
Volume 84,
issue 1
页码: 155-160
ISSN:0002-8487
年代: 1955
DOI:10.1577/1548-8659(1954)84[155:STIBT]2.0.CO;2
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
Sterility was observed in female brook trout that were treated with sulfamerazine at frequent intervals for 2 years to control endemic furunculosis. Feeding sulfamerazine for a period of 8 months caused massive kidney damage similar to that observed in humans who develop allergies to “sulfa” drugs. Kidney damage of the type observed would probably cause renal insufficiency which would handicap any physiological function including reproduction. Feeding sulfonamides for periods up to 13 weeks did not produce kidney damage.
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