The behavior of biological materials at different sites of implantation
作者:
Edward J. Kaminski,
Richard J. Oglesby,
Norman K. Wood,
James Sandrik,
期刊:
Journal of Biomedical Materials Research
(WILEY Available online 1968)
卷期:
Volume 2,
issue 1
页码: 81-88
ISSN:0021-9304
年代: 1968
DOI:10.1002/jbm.820020106
出版商: John Wiley&Sons, Inc.
数据来源: WILEY
摘要:
AbstractAdult albino rabbits were implanted with disks of 316 and 304 stainless steel in the subperiosteum of the anterior calvarium and the left mandible and in the left paravertebral and thigh muscles. The corresponding opposite sites were sham operated. The histopathological slides revealed that there was variation in thickness of the membrane in sections of both the paravertebral and thigh muscles; one side showing greater reaction than the other, which corresponded with the appearance of the implants. Sections of the calvarium revealed minimal bone and soft tissue reaction, although the implants showed corrosion compatible with soft tissue sites. The mandibular sections revealed extensive bone tissue reactions with minimum masseter muscle reactions, but the appearance of the implants due to corrosion was different than those of all other sites. Moderate eosinophilic infiltration was observed in sections containing deposits of corrosion products.
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