Natural predation on nymphs and adults of the cotton fleahopper,Pseudatomoscelis seriatus(Reuter), was assessed during 108 h of visual observation in an insecticide-free cotton field in central Texas. Predaceous arthropods of 13 species (from nine families) were observed to forage on the fleahopper. More than 80% of the predation events observed were attributable to spiders. The striped lynx spider,Oxyopes salticusHentz, was dominant among the predators observed eating fleahoppers (15 records of feeding in action). Cotton fleahoppers composed ≈25% of the total prey ofO. salticusduring June and July. It was estimated during midseason that once every 4 d, one O.salticuswould kill one cotton fleahopper. The assessment of the killing power ofO. salticus,based on the predation rate and the predator-to-prey ratio (i.e., number ofO. salticusindividuals per fleahopper), suggests that these spiders are important mortality agents of the cotton fleahopper (≥15% prey mortality per day in the middle of the growing season). Additional fleahopper mortality is attributable to other predaceous arthropods such asPeucetia viridans(Hentz) (Oxyopidae), jumping spiders (Salticidae), crab spiders (Thomisidae), web-building spiders (Araneidae, Dictynidae, Theridiidae), damsel bugs (Nabidae), and ants (Formicidae).