In brief:The authors continue their discussion of the physiological responses and adaptations that occur as a result of resistance training. (The discussion began in part 2; part 1 presented the basics of resistance training.) Body composition, neural and cardiovascular adaptations, serum lipid profile, blood pressure, and the endocrine system are covered in this article. The conclusion is that conventional weight training brings about little change in endurance capabilities, but that high-volume, low-load training enhances endurance capabilities and may cause serum lipid profile changes that reduce cardiovascular risk.