This article summarizes the results of a national survey of salary, staffing, and professional practice patterns in oncology nursing conducted by the Oncology Nursing Society. The respondents represent a wide geographic distribution, and data were analyzed in the aggregate, as well as by American Hospital Association (AHA) regions, to allow for predictions of regional as well as national trends. This article reports on national and regional trends in salaries for entry-level and experienced practitioners; salary patterns for agency and float pool nurses; and the methods for awarding salary increases to nursing personnel in the past year. National trends in a variety of personnel practices affecting oncology nursing (e.g., shifts, self-scheduling, tuition reimbursement, and certification) are also presented. The data in this study come from a broad-based and geographically well-distributed sample that allows for meaningful national comparisons.