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FUNDAMENTAL AND CLINICAL ASPECTS OF ANTI NEUTROPHIL CYTOPLASMIC ANTIBODIES (ANCA)

 

作者: HagenE. C.,   BallieuxB. E.P.B.,   DahaM. R.,   Van EsL. A.,   Van Der WoudeF. J.,  

 

期刊: Autoimmunity  （Taylor Available online 1992）
卷期: Volume 11, issue 3  

页码: 199-207

 

ISSN:0891-6934

 

年代: 1992

 

DOI:10.3109/08916939209035155

 

出版商: Taylor&Francis

 

关键词: Anti neutrophil cytoplasmic antibodies;vasculitis;glomerulonephritis

 

数据来源: Taylor

 

摘要:

Anti-neutrophil cytoplasmic antibodies (ANCA) are associated with different forms ofboth primary and secondaryvasculitis and glomerulonephritis. These antibodies are directed against different enzymes located in granulocyte granules. In this review ANCA-related antigens and solid phase assays for ANCA detection will be discussed. Furthermore, we will address the clinical relevance of ANCA and will deliberate on their possible pathogenic implications.

 

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