首页   按字顺浏览 期刊浏览 卷期浏览 NMR study of conformation and configuration in C‐20‐substituted 5β,14β‐pregnanes, 5β‐pr...
NMR study of conformation and configuration in C‐20‐substituted 5β,14β‐pregnanes, 5β‐pregn‐14‐enes and 21‐nor‐5β,14β‐pregnanes

 

作者: Kirk Marat,   J. F. Templeton,   Yangzhi Ling,  

 

期刊: Magnetic Resonance in Chemistry  （WILEY Available online 1993）
卷期: Volume 31, issue 1  

页码: 17-22

 

ISSN:0749-1581

 

年代: 1993

 

DOI:10.1002/mrc.1260310106

 

出版商: John Wiley&Sons, Ltd.

 

关键词: NMR;Coupling constants;NOE;Conformation;Configuration C‐20 substituted 5β,14β‐pregnanes,5β‐pregn‐14‐enes and 21‐nor‐5β,14β‐pregnanes

 

数据来源: WILEY

 

摘要:

AbstractCoupling constants and nuclear Overhauser effect measurements were used to establish the C‐20 configuration and the conformation about the C‐17C‐20 bond in a series of sixteen C‐20‐substituted 5β,14β‐pregn‐14‐enes. In the 14β‐pregnane series the conformation of the C‐17 side‐chain is variable, whereas in the pregnenes the side‐chain adopts a conformation in which H‐17 isantito H‐20. The C‐17 side‐chain conformation of two 21‐nor‐5β,14β‐pregnanes was also determined. In the 21‐nor compounds a C‐20 hydroxyl adopts a conformationant

 

点击下载:  PDF (539KB)



返 回