Cholesterol-Lowering and HDL-Raising Properties of Lecithinated Soy Proteins in Type II Hyperlipidemic Patients
作者:
C.R. Sirtori,
C. Zucchi-Dentone,
M. Sirtori,
E. Gatti,
G.C. Descovich,
A. Gaddi,
L. Cattin,
P.G. Da Col,
U. Senin,
E. Mannarino,
G. Avellone,
L. Colombo,
C. Fragiacomo,
G. Noseda,
S. Lenzi,
期刊:
Annals of Nutrition and Metabolism
(Karger Available online 1985)
卷期:
Volume 29,
issue 6
页码: 348-357
ISSN:0250-6807
年代: 1985
DOI:10.1159/000176991
出版商: S. Karger AG
关键词: Textured soy proteins;Type II hyperlipoproteinemia;Lecithin;High-density lipoprotein cholesterol
数据来源: Karger
摘要:
Plasma lipoprotein changes were evaluated in 65 type II patients undergoing sequential 4-week dietary treatments with: (I) standard low-lipid diet; (II) low-lipid diet with total replacement of animal proteins with textured soy proteins containing 6 % of lecithin (L-TVP); (III) standard low-lipid diet; (IV) low-lipid diet with a 50% substitution of animal proteins with L-TVP. Total cholesterolemia was significantly reduced in both periods of L-TVP administration: -18.6% during phase II (total replacement) and -13.2% during phase IV (partial replacement). High-density lipoprotein (HDL) cholesterol levels tended to increase during L-TVP administration. However, only patients in the mid- and low tertiles for HDL cholesterolemia showed a significant increase of HDL levels during L-TVP. This ‘normalizing’ activity of L-TVP on plasma lipoproteins, even when administered as a partial dietary substituent, may be of clinical interest for subgroups of patients at high vascular r
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