AbstractAn integrated Fate Model has been developed for predicting the fate of organics in a wastewater treatment plant. The Fate Model has been validated using experimental data from a pilot‐scale facility. The biodegradation kinetic constants for some compounds in the Fate Model were estimated using the group contribution approach. The Fate Model has been compared with other existing models in the literature. Potential applications of the Fate Model include assessment of volatile organic compound (VOC) emissions from a wastewater treatment plant, evaluate pretreatment requirements prior to discharge to the sewer system, predict concentrations of toxic compounds on sludges, and provide a general framework for estimating the removal of toxic compounds during activated sludge treatmen