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Peripheral Nonulcerative Keratitis as a Presenting Sign of Microscopic Polyangiitis

 

作者: Jason Darlington,   Mark Mannis,   William Segal,   Vahid Feiz,   Donald Klug,  

 

期刊: Cornea  （OVID Available online 2001）
卷期: Volume 20, issue 5  

页码: 522-524

 

ISSN:0277-3740

 

年代: 2001

 

出版商: OVID

 

关键词: Peripheral nonulcerative keratitis;Peripheral ulcerative keratitis;Microscopic polyangiitis;Systemic vasculitis;Necrotizing glomerulonephritis;Antimyeloperoxidase antibody;Antineutrophil cytoplasmic antibody

 

数据来源: OVID

 

摘要:

Purpose.To report a 16-year-old woman who had peripheral keratitis as a presenting sign of microscopic polyangiitis (MPA), which rapidly progressed to acute renal failure.Method.Case report.Results.The patient's vasculitis was diagnosed by renal biopsy, which was evaluated with histologic, immunofluorescence, and electron microscopy. The diagnosis was confirmed by laboratory study, which showed a positive antimyeloperoxidase antibody.Conclusion.MPA may rarely present with ocular findings and should be considered in the differential diagnosis when a patient has peripheral keratitis.

 

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