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Analysis of ribosomal and alphoid repetitive DNA by fiber-FISH

 

作者: C. Shiels,   C. Coutelle,   C. Huxley,  

 

期刊: Cytogenetic and Genome Research  （Karger Available online 1997）
卷期: Volume 76, issue 1-2  

页码: 20-22

 

ISSN:1424-8581

 

年代: 1997

 

DOI:10.1159/000134504

 

出版商: S. Karger AG

 

数据来源: Karger

 

摘要:

We have used fluorescence in situ hybridization to extended DNA fibers (fiber-FISH) to analyse the α-satellite and rDNA arrays on a human chromosome 22. The rDNA could be seen as a string of signals spanning about 430 kb. The bulk of the alphoid DNA was found in a single large array of about 2.6 Mb

 

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