Sensory‐specific satiety‐related olfactory activation of the human orbitofrontal cortex
作者:
J O'Doherty,
E Rolls,
S Francis,
R Bowtell,
F McGlone,
G Kobal,
B Renner,
G Ahne,
期刊:
NeuroReport
(OVID Available online 2000)
卷期:
Volume 11,
issue 4
页码: 893-897
ISSN:0959-4965
年代: 2000
出版商: OVID
关键词: Cingulate cortex;Emotion;Insula;Olfaction;Orbitofrontal cortex;Pleasant;Sensory-specific satiety
数据来源: OVID
摘要:
When a food is eaten to satiety, its reward value decreases. This decrease is usually greater for the food eaten to satiety than for other foods, an effect termed sensory-specific satiety. In an fMRI investigation it was shown that for a region of the orbitofrontal cortex the activation produced by the odour of the food eaten to satiety decreased, whereas there was no similar decrease for the odour of a food not eaten in the meal. This effect was shown both by a voxel-wise SPM contrast (p< 0.05 corrected) and an ANOVA performed on the mean percentage change in BOLD signal in the identified clusters of voxels (p< 0.006). These results show that activation of a region of the human orbitofrontal cortex is related to olfactory sensory-specific satiety.
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