Therapy of Infections with Cefazolin
作者:
Aksel Schreiner,
Asbjørn Digranes,
Erik Hamre,
Harald Nygaard,
期刊:
Chemotherapy
(Karger Available online 1976)
卷期:
Volume 22,
issue 6
页码: 381-389
ISSN:0009-3157
年代: 1976
DOI:10.1159/000221950
出版商: S. Karger AG
关键词: Cephalosporins;Cefazolin;Lower respiratory tract infections;Urinary tract infections
数据来源: Karger
摘要:
16 patients with acute urinary tract infections, 6 with acute lower respiratory tract infections and 3 with miscellaneous infections were treated with 1 g cefazolin parenterally 3 times daily. All patients, except one in whom therapy was discontinued, were cured. Both intramuscular and intravenous administration resulted in high-peak serum levels, and concentrations after 8 h were still inhibitory to relevant pathogens. The drug was well tolerated and caused, after intramuscular injection, probably less pain than does cephalotin. Cefazolin is a rational choice of therapy in severe cases of acute urinary, respiratory, and other infections.
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