Toxicological evaluation and pharmacokinetic profile of beta‐hydroxypropionitrile in rats
作者:
M. W. Sauerhoff,
W. H. Braun,
J. C. Ramsey,
C. G. Humiston,
G. C. Jersey,
期刊:
Journal of Toxicology and Environmental Health
(Taylor Available online 1976)
卷期:
Volume 2,
issue 1
页码: 31-44
ISSN:0098-4108
年代: 1976
DOI:10.1080/15287397609529415
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
Beta‐hydroxyproplonitrile (β‐HPN) was incorporated in the drinking water of rats in order to define the toxicological effects associated with repeated daily exposure to this compound. Parameters evaluated were appearance and demeanor, mortality, body weight, food consumption, water consumption, hematology, terminal organ weights and organ to body weight ratio, and gross and microscopic pathology of tissues. No untoward effects were associated with the ingestion of β‐HPN at the dose levels utilized.
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