Recurrence of Focal-Segmental Glomerulosclerosis in Kidney Transplant Patients on Ciclosporin
作者:
R. Marcen,
J.F. Navarro,
F. Mampaso,
L. Orofino,
A. Gonzalo,
J.L. Teruel,
J. Ortuño,
期刊:
Nephron
(Karger Available online 1994)
卷期:
Volume 68,
issue 4
页码: 497-499
ISSN:1660-8151
年代: 1994
DOI:10.1159/000188313
出版商: S. Karger AG
关键词: Ciclosporin A;Focal-segmental glomerulosclerosis;Glomerulonephritis;Kidney-transplant
数据来源: Karger
摘要:
Two patients on maintenance hemodialysis after terminal renal failure due to nephrotic syndrome and biopsy-proven focal-segmental glomerulosclerosis received three cadaver renal allografts. Immediate recurrence of nephrotic syndrome was observed. In two transplants immunosuppression consisted of ciclosporin A and low-dose steroids. One patient was unsuccessfully treated with immunoadsorption after the second transplant. All grafts were lost because of uncontrolled nephrotic syndrome. Renal allograft biopsy specimens showed findings indicating recurrence of the original disease.
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