Evaluation of the proportionate mortality index in the presence of multiple comparisons
作者:
Howard E. Rockette,
Vincent C. Arena,
期刊:
Statistics in Medicine
(WILEY Available online 1987)
卷期:
Volume 6,
issue 1
页码: 71-77
ISSN:0277-6715
年代: 1987
DOI:10.1002/sim.4780060109
出版商: Wiley Subscription Services, Inc., A Wiley Company
关键词: Mortality index;Multiple comparisons;Simulation
数据来源: WILEY
摘要:
AbstractWe investigate the frequency in occupational studies of falsely identifying significantly elevated cause‐specific mortality in the presence of multiple comparisons. When one investigates a standard battery of causes of death, use of a standardized mortality ratio as a summary index results in an excessive experimental error rate, but one can control the error rate with use of standard procedures that limit the type I error. When a major disease category for an occupational cohort has a lower rate than expected, then with use of a proportionate mortality ratio as a summary index, the standard procedures for control of the type I error are inadequate. In this situation, use of a proportionate mortality ratio as a summary index is likely to result in the false identification of an excess cause‐specific mortality more often than previously acknowled
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