Effects of Carbohydrate-Active Steroids and ACTH on Visually-Evoked Responses in Patients with Adrenal Cortical Insufficiency
作者:
M.S. Buchsbaum,
R.I. Henkin,
期刊:
Neuroendocrinology
(Karger Available online 1975)
卷期:
Volume 19,
issue 4
页码: 314-322
ISSN:0028-3835
年代: 1975
DOI:10.1159/000122452
出版商: S. Karger AG
关键词: Adrenal cortical steroids;ACTH;Visually-evoked potentials;Average evoked response;Adrenal cortical insufficiency
数据来源: Karger
摘要:
Visual average evoked responses (AERs) to 4 intensities of light were studied in 5 patients with adrenal cortical insufficiency. Patients were tested off all medications, on ACTH while off all medications, and during replacement with carbohydrate-active steroids. Off treatment, when steroid levels were low, AERs were of small amplitude and short latency. Treatment with ACTH alone decreased the amplitude/intensity response, suggesting extra-adrenal effects. Both with amplitude and latency effects, stimulus intensity was an important parameter in determining steroid and ACTH effects.
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